Colorectal Cancer
Conditions
Keywords
screening colonoscopy, attendance, response, colorectal cancer
Brief summary
The attendance rate to population based primary screening colonoscopy within NordICC trial (The Nordic-European Initiative on Colorectal Cancer, NCT00883792) in Poland is roughly 33%. The aim of this study is to compare the effect of two different time schedules for sending invitations and reminding letters to a pre-specified colonoscopy appointment. 1,600 screening naive men and women 55 to 64 years of age are randomly assigned in a 1:1 ratio to receive invitation and reminder 6 and 3 weeks (SIX and THREE group) or 4 and 2 weeks (FOUR and TWO group) prior to pre-specified screening colonoscopy appointment date. Outcome measures are participation in screening colonoscopy within 6 months from the date of invitation, response and acceptance rate before sending a reminder. The study is powered to detect 7% difference in participation in screening colonoscopy.
Interventions
OTHERSix and three time schedule
Invitation letter sent 6 weeks and reminder 3 weeks before a pre-specified screening colonoscopy appointment date.
OTHERFour and two time schedule
Invitation letter and reminder sent 4 and 2 weeks before pre-specified screening colonoscopy appointment date.
Sponsors
National Center for Research and Development, Poland
Maria Sklodowska-Curie National Research Institute of Oncology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
Individuals aged 55-64 years living in Warsaw area randomly drawn from Population Registry and randomized to the screening arm of the NordICC trial.
Exclusion criteria
* Resident abroad * Return of unopened letter of invitation and/or reminder (address unknown) * Message from neighbour/family/post office on death of screenee (not updated in Population Registry).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Participation rate | 6 months from the date of sending invitation letter | Percentage of attenders to screening colonoscopy. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Acceptance rate in SIX &THREE group | 3 weeks from the date of sending invitation letter | Percentage of invitees who agreed (by phone or letter) to participate in screening colonoscopy before sending a reminder |
| Acceptance rate in FOUR&TWO group | 2 weeks from the date of sending invitation letter, respectively | Percentage of invitees who agreed (by phone or letter) to participate in screening colonoscopy before sending a reminder |
| Response rate in SIX&THREE group | 3 weeks from the date of sending invitation letter | Percentage of invitees who responded (by phone or letter) before sending a reminder |
| Response rate in FOUR&TWO group | 2 weeks from the date of sending invitation letter | Percentage of invitees who responded (by phone or letter) before sending a reminder |
Countries
Poland
Outcome results
None listed