Inspiratory Resistive Loading and Diaphragm Fatigue

Inspiratory Resistive Loading and Diaphragm Fatigue in Healthy Individuals and Individuals With Recurrent Low Back Pain

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01505517

Enrollment

Registered

2012-01-06

Start date

2011-01-31

Completion date

2012-06-30

Last updated

2013-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diaphragm Fatigue, Healthy, Low Back Pain

Brief summary

The aim of the study is to clarify whether specific loading of the inspiratory muscles induces contractile fatigue of the diaphragm muscle in healthy individuals and individuals with recurrent low back pain.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

individuals with low back pain: * Age: 18-35 years old * At least 1 year of low back pain with/without referred pain in buttock/thigh * At least 3 episodes of disabling low back pain * At least a score of 20% on the Oswestry Disability Index * Willingness to sign the informed consent Inclusion Criteria healthy individuals: * Age: 18-35 years old * No history of low back pain * A score of 0% on the Oswestry Disability Index * Willingness to sign the informed consent

Exclusion criteria

* History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant * One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder, respiratory disease, pregnancy * Radicular symptoms * Not Dutch-speaking * Strong opioids * Neck pain * Smoking history

Design outcomes

Primary

Measure	Time frame	Description
transdiaphragmatic pressure	18 months	transdiaphragmatic pressure measurement in response to bilateral anterior magnetic phrenic nerve stimulation before and after an inspiratory resistive loading protocol

Countries

Belgium

Outcome results