Noninvasive Brain Stimulation for Stroke

Noninvasive Brain Stimulation for Stroke Improvement

Status

Suspended

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01503073

Acronym

NIBSstroke

Enrollment

200

Registered

2012-01-02

Start date

2008-01-31

Completion date

2030-12-31

Last updated

2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

stroke

Brief summary

Noninvasive brain stimulations will be used in acute and chronic stroke patients to improve a variety of functions.

Detailed description

Noninvasive brain stimulations (NIBS) will be used in acute and chronic stroke patients to improve a variety of functions such as motor functions, cognitive functions, ... NIBS will be applied in a placebo-controlled, double-blind, randomised fashion. Behavioural data will be collected before and after NIBS, as well as brain functional imaging data.

Interventions

DEVICEtdcs (ELDITH, Neuroconn, Ilmenau, Germany)

transcranial direct current stimulation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* stroke with at least slight deficit

Exclusion criteria

* epilepsy * contraindication to tDCS and/or to fMRI * presence of metal in the head * unability to understand / complete behavioural tasks * chronic intake of alcohol or recreative drugs * major health condition * presence of pacemaker * pregnancy

Design outcomes

Primary

Measure	Time frame	Description
change in function before/after tDCS	Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months	any brain function impaired by stroke

Secondary

Measure	Time frame	Description
change in neuroimaging and neurophysiological before/after tDCS	Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months	1. noninvasive neuroimaging : brain activity studied by means of fMRI 2. noninvasive neurophysiological measure : TMS, EEG,evoked potentials, EMG

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026