Breast Cancer
Conditions
Keywords
Pregnant women
Brief summary
This is a non-interventional, retrospective, multicentre study involving women having had a breast cancer during their pregnancy, diagnosed between 2000 and 2014 (cases) and non-pregnant women having had a breast cancer between 2000 and 2009 (controls).
Detailed description
Investigators will explain the purpose of the study to the eligible patients, still alive, and will inform them verbally and in writing, using the information note, of their possibility of refusal. No information will be made for deceased patients. The investigators will complete the case report forms on paper and then will send them by mail.
Interventions
None listed
Sponsors
Centre Oscar Lambret
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Women aged 18 or over * Confirmed histological diagnosis of invasive breast cancer * No known metastasis * For the cases : * Patients pregnant at the time of the first diagnosis * 1st diagnosis between 2000 and 2014 * For the controls : * Patients not pregnant at the time of the first diagnosis * 1st diagnosis between 2000 and 2009
Exclusion criteria
* Patients who have undergone an induced abortion after the diagnosis of breast cancer * Patients with a history of breast cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | 5 years | The overall survival corresponds to the time elapsed between the breast cancer diagnostic date and the death date. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the support of breast cancer cases occured during pregnancy | 5 years | Description of the anti-tumor treatment (surgery, radiotherapy, chemotherapy, hormone therapy, targeted therapy), of the imaging performed and of the childbirth (programmed or not, vaginal or caesarean section, baby's condition at birth, etc.). |
| Tumor characteristics | 5 years | Description of the tumor characteristics on the diagnostic biopsy or on the surgical specimen : histological type, Her2 status, hormone receptor status, etc. |
| Disease-free survival | 5 years | The disease-free survival is calculated from the time elapsed between the breast cancer diagnostic date and the first recurrence of the disease. |
| Case-control comparison | 5 years | Comparison of the tumoral characteristics, the patient care and the prognosis of women with breast cancer appeared during a pregnancy, with non-pregnant women of the same age. |
Countries
France
Outcome results
None listed