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A Longitudinal Study in 1st Degree Relatives of Parkinson's Disease (PD) Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01502384
Enrollment
100
Registered
2011-12-30
Start date
2012-01-31
Completion date
Unknown
Last updated
2011-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's Disease

Keywords

healthy 1st degree relatives of pd patients

Brief summary

This is a longitudinal study in healthy 1st degree relatives of patients with Parkinson's Disease (PD) carriers of a genetic mutation in genes that are known to increase the risk for PD. The purpose of this study is to explore the association between genetic mutations in the known genes and early preclinical symptoms such as motor, sensory, autonomic, behavioral and cognitive functions.

Interventions

motor and cognitive functions

Sponsors

Beth Israel Medical Center
CollaboratorOTHER
Columbia University
CollaboratorOTHER
Tel-Aviv Sourasky Medical Center
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT

Eligibility

Sex/Gender
ALL
Age
35 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy 1ST degree relatives of PD patients with known genotype that participated in an earlier genetic study at the sourasky medical center.

Exclusion criteria

* subjects with cognitive decline by the parameters defined in DSM- IV * subjects with psychiatric disorder * subjects unable to sign a consent form

Countries

Israel

Contacts

Primary ContactAnat Mirelman, PhD
anatmi@tasmc.health.gov.il972-3-6974958

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026