Pancreatic Tumors
Conditions
Brief summary
Endoscopic Ultrasound (EUS)-guided biopsy is the most ideal technique for evaluating a growth in the pancreas. EUS-guided biopsies yield a definitive diagnosis in greater than 80% of cases. In 15-20% of the cases, a definitive diagnosis cannot be made despite multiple attempts. One of the reasons why a diagnosis cannot be made is due to the focal location of the cancer; i.e., the cancer can be situated in a corner of a big mass and the needle fails to sample the cancer cells. The fanning technique is a method where the needle moves in multiple directions within a mass and therefore there is a better chance of the cancer cells being sampled compared to the standard technique where the needle moves in only one direction. The diagnostic performance of both these techniques has not been compared in a randomized fashion.
Detailed description
Fanning technique: Fine Needle Aspiration (FNA) performed in multiple directions within a mass. Standard technique: FNA performed in unidirectional fashion.
Interventions
PROCEDUREStandard
FNA in a single plane
PROCEDUREFanning
FNA in multiple planes
Sponsors
Shyam Varadarajulu
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Age \> 19 years * Solid Pancreatic Mass Lesions
Exclusion criteria
* Age \< 19 years * Coagulopathy * Unable to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic accuracy | 2 months | The number of pancreatic masses that are correctly diagnosed with each needle type |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of passes for diagnosis | 2 months | Number of passes required to acquire tissue diagnosis using each needle type |
Countries
United States
Outcome results
None listed