HIV
Conditions
Keywords
HIV prevention, HSV-2, Schooling, Kenya, Orphans, School support
Brief summary
The purpose of this study is to test whether school support can keep adolescent Kenyan orphans in school, reduce sexual risk behaviors, and prevent HIV /HSV-2 infection.
Detailed description
This study examines the impact of school support as a structural intervention, tested among adolescent orphans in Siaya District, Nyanza Province, Kenya. Aims for the proposed study are: 1) To experimentally test whether providing comprehensive school support to Kenyan orphaned boys and girls will reduce school dropout, reduce sexual risk behaviors, and prevent HIV/HSV-2 infection; 2) To conduct a process evaluation of the implementation of the program; and 3) To conduct comparative cost effectiveness analyses, specifying the intervention's cost and return on investment as evidenced by cost per unit improvement in the primary outcomes of school enrollment, delay of sexual debut and prevention of risk behaviors and HIV/HSV-2 infection, as well as by gains in health-related quality of life.
Interventions
BEHAVIORALSchool Support Intervention
Comprehensive school support is provided that includes payment of school fees, school uniform, and a nurse researcher who monitors attendance and addresses problems that may lead to school absence and dropout.
Sponsors
National Institute of Mental Health (NIMH)
Moi University
University of North Carolina, Chapel Hill
Pacific Institute for Research and Evaluation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Orphan (one or both parents deceased) * In Grade 7 or 8 in a primary school participating in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HSV-2 Incidence | 3 years |
| Change from baseline in ever had sexual intercourse at 3 years | Baseline and 3 years |
| HIV Incidence | 3 years |
| Dropped out of school | From date of randomization until drop out from school, up to 3 years |
| Change from baseline in ever had sexual intercourse at 1 year | Baseline and 1 year |
| Change from baseline in ever had sexual intercourse at 2 years | Baseline and 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Health-related quality of life | Baseline and 1 year |
| Ever married or ever pregnant | From date of randomization until marriage or preganancy, up to 3 years |
Countries
Kenya, United States
Outcome results
None listed