Infertility
Conditions
Brief summary
The recent controversy regarding the use of pill for cycle planning in GnRH antagonists IVF cycle has driven the search for new ways to plan IVF cycles in order to avoid weekends or to equally distribute the workload. Recently, mid-late luteal phase oral estrogens seem to be as good as the pill. The investigators will compare OCP vs oral estrogens to plan the initiation of IVF cycles.
Interventions
30 microgram of ethinylestradiol plus levonorgestrel daily for 12 to 16 days
DRUGEstradiol valerate
4mg estradiol valerate from cycle day 20 till the day before the initiation of the cycle
Sponsors
IVI Madrid
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* 1st or 2nd IVF cycle * BMI \<30 kg/m2 * regular menstrual cycles * basal FSH \<10IU and E2 \<60pg/mL
Exclusion criteria
* polycystic ovaries * endometriosis * previous ovarian surgery * previous low ovarian response
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Implantation rate | 20 days after the embryo transfer | number of embryonic sacs visible by ultrasound divided by the number of embryos transferred |
Countries
Spain
Outcome results
None listed