Myositis, Primary Sjogren´s Syndrome
Conditions
Brief summary
Exercise may improve physical capacity and health parameters in Primary Syndrome´s Sjogren, Myositis and Takayasu's Arteritis. Therefore, this study aims to investigate the role of an exercise training program in patients with Primary Syndrome´s Sjogren, Myositis and Takayasu's Arteritis.
Interventions
OTHERExercise training
Sjöegren arm: 30-60 minutes of combined aerobic and strength exercises, twice a week, moderate intensity. Myositis arm: 30 minutes of resistance training combined partial blood flow restriction, twice a week, low intensity. Takayasu's arteritis arm: 30-50 minutes of aerobic, twice a week, moderate intensity.
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Physically inactive * Stable drugs regime for at least three months
Exclusion criteria
* Other rheumatic diseases * Physical disability that prevent the patient to perform the physical tests * Severe pulmonary disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Aerobic Capacity | Twelve weeks | Maximum Oxygen Consumption (VO2Max) |
| Muscle strength | Twelve weeks | — |
| Quality of life | Twelve weeks | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum anti-inflammatory cytokines | Twelve weeks | Interleukin-10 |
| Serum pro-inflammatory cytokines | Twelve weeks | Interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor-a (TNF-a) |
| Serum inflammatory markers | Twelve weeks | erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), aldolase |
Countries
Brazil
Outcome results
None listed