Quality Study of Anesthetic Technique on Breast Cancer Surgery

Effect of Anesthetic Technique on Pain、 Recovery and Satisfaction in Women Undergoing Breast Surgery

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01499836

Acronym

PQSAT

Enrollment

101

Registered

2011-12-26

Start date

2012-01-31

Completion date

2013-06-30

Last updated

2014-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain, Quality of Recovery, Satisfaction

Brief summary

Previous studies have shown that paravertebral block (PVB) has the potential to reduce pain and side effects after breast surgery when used in addition to general anesthesia or sedation.The investigators would like to further discern the impact of GA or PVB on the postoperative QoR, pain and satisfaction.

Interventions

OTHERPVB

paravertebral block

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patient has a physical status between ASA I and III * Female * 18 - 70 years of age * Patients able to read a newspaper in Chinese. * Elective unilateral wide excision/simple mastectomy and SLNB/ALND * Patient has signed an informed consent * Without contraindication of GA or PVB * Body mass index (BMI) less than 24 kg/m2

Exclusion criteria

* ASA \> III * inability to provide informed consent * Bleeding disorders * Contraindications to nonsteroidal anti-inflammatory drugs (NSAIDs) * Allergy to amide-type local anesthetics or NSAIDs * Infection at the thoracic paravertebral injection site * Pregnancy or breast-feeding * Severe spine or chest wall deformity * body mass index equal to or more than 24 kg/m2 * patients with major psychosis or drug and alcohol abuse * patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease * Patients with significant visual impairment or other physical disability that precludes complete cooperation

Design outcomes

Primary

Measure	Time frame
quality of recovery	postoperative 6 hour and postoperative day(POD)1

Secondary

Measure	Time frame
adverse events	POD1
Number of patients with a technique failure of the PVB	during operation
NRS pain score	postoperative 1 hour, 6 hour, and POD1
Satisfaction	POD1

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026