Effects of Different Coffee Amounts on Energy Intake, Appetite, Glucose Metabolism and Inflammatory Markers

The Effect of Different Amounts of Coffee on Dietary Intake, Appetite-related Feeling, Appetite Hormones, Glucose Metabolism and Inflammatory Markers of Normal Weight and Overweight/Obese Individuals

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01495754

Enrollment

Registered

2011-12-20

Start date

2011-01-31

Completion date

2011-06-30

Last updated

2011-12-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation, Obesity

Keywords

coffee, overweight/obese, appetite, energy intake, inflammation, glucose metabolism, randomized controlled trial

Brief summary

The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and glucose metabolism compared to water consumption in normal weight and overweight/obese participants.

Interventions

OTHERcoffee

Comparison of different amounts of coffee

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* apparently healthy * habitual coffee drinkers (\>= 1cup of coffee/day)

Exclusion criteria

* smokers * restrained eaters (as this was evaluated using the Dutch Eating Behaviour Questionnaire) * those who reported slimming or any other dietary regime * athletes * participants with a known diagnosis of either hypertension, diabetes, impaired glucose tolerance or a fasting blood glucose concentration above 125 mg/dl * subjects on medication for hypertension or on medication known to alter glucose metabolism * subjects who were on medication that may have an impact on appetite and sensory functioning or who reported a metabolic or * endocrine disease, * gastrointestinal disorders, * a history of medical or surgical events that may have affected the study outcomes

Design outcomes

Primary

Measure	Time frame
markers of glucose metabolism	fasting (-15 min)
energy intake ad libitum	180 min after breakfast/drink consumption
total energy intake	One day
appetite feelings	fasting (-15 min)
appetite hormones	fasting (-15 min)
markers of inflammation	fasting (-15 min)

Secondary

Measure	Time frame
% carbohydrates ad libitum	180 min after breakfast/drink consumption
% carbohydrates total day	One day
% protein ad libitum	180 min after breakfast/drink consumption
% protein total day	One day
% fat	180 min after breakfast/drink consumption
% fat total day	One day

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026