Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Status

Withdrawn

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01495715

Enrollment

Registered

2011-12-20

Start date

Unknown

Completion date

Unknown

Last updated

2014-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leber's Hereditary Optic Neuropathy

Brief summary

The objective of the study is to determine whether administration of idebenone can shorten the time to improvement of visual acuity in patients with chronic vision loss due to LHON.

Interventions

DRUGIdebenone

DRUGPlacebo

Eligibility

Sex/Gender

ALL

Age

10 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Age \> or equal 10 years and \< 65 years * Impaired visual acuity in affected eyes due to LHON: Visual acuity in best eye \>0.4 logMAR * No explanation for visual loss besides LHON

Exclusion criteria

* Any previous use of idebenone * Participation in another clinical trial of any investigational drug within 3 months prior to Baseline * Previous participation in Study SNT-II-003 (RHODOS) for idebenone.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026