Skip to content

The Effect of Marketing Variable on Effect of Active Drugs

The Effect of Price and Marketing Variable on the Pain Controlling Effect of Active Drugs in a Clinical Trial.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01493908
Enrollment
220
Registered
2011-12-16
Start date
2012-01-31
Completion date
2013-06-30
Last updated
2011-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Placebo effect;, Pain; Analgesic;, Electrical shock, control in healthy volunteers

Brief summary

The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches. A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance. In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication. In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist. The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.

Interventions

DRUGHigh price

Acetaminophen label as high price

DRUGLow price

Acetaminophen label as low price

DRUGLow price participants aware paying part

Acetaminophen label as low price; participants aware they are paying part of the full price

DRUGNo price

acetaminophen. No price - price issue not introduced to participants.

DRUGFree of charge

Acetaminophen. participants aware the product is free of charge

Sponsors

Hadassah Medical Organization
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy Volunteer participants will be between the ages of 18 and 65

Exclusion criteria

* Candidates who have had a history of cardiac problems, epilepsy, diabetes, or are pregnant will be excluded. * Taking no pain medication at the time of the experiment.

Design outcomes

Primary

MeasureTime frameDescription
pain thresholds1hourParticipants will rank their pain thresholds individually and subjectively for a series of pulses. Each participant will experience a series of pulses with random intensity. Pulse intensity will range within 30-90% of the participants maximal level.

Countries

Israel

Contacts

Primary ContactAmnon - Lahad, MD, MPH
amnonl@cc.huji.ac.il+972-2-6758505
Backup ContactHadas - Lemberg, PhD
lhadas@hadassah.org.il00 972 2 6777572

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026