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Chronic Sleep Restriction

Chronic Sleep Restriction: Neurobehavioral and Physiological Responses

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01493661
Acronym
CSR
Enrollment
20
Registered
2011-12-16
Start date
2011-12-31
Completion date
2015-02-28
Last updated
2016-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other Conditions That May Be A Focus of Clinical Attention

Keywords

Sleep, Polysomnography, Reaction Time, Sleep Deprivation, Psychophysiology, Chronic sleep restriction, healthy, without sleep complaints

Brief summary

Sleep is a physiological state considered essential for health and human survival. The prevalence of chronic sleep restriction has increased in modern society, as well as the effects of the same health concerns about various aspects, including the physiological and neurobehavioral. The objective of this study is to identify the neurobehavioral and physiological responses of healthy men with different needs of total sleep time (TST) submitted to chronic sleep restriction. Participants in this study will be 30 male volunteers, aged between 20 and 35 years, divided into three groups: Group 1 (n = 10) with TST ≤ 6 hours (h), Group 2 (n = 10) with TST ≥ 9h and Group 3 (n = 10): TST with between 7 and 8h. The TST will be established by the constant and continuous use of actigraphy for 10 days prior to the onset of the experimental protocol. All volunteers will undergo medical and polysomnography (PSG) examination to detect the presence or not of changes in sleep as well as other health problem that prevents their participation in the study. The experimental protocol consists of a basal night of sleep, five consecutive nights of chronic sleep restriction to 25% of TST in the beginning night and a night of recovery, which will be allowed to sleep the sleep pattern. Each night will have PSG monitoring and when wake up in each day, the volunteer will undergo tests to assess the physiological and neurobehavioral variables. The significance level will be 5% (p ≤ 0.05).

Interventions

All volunteers will undergo 25% of sleep restriction of their total sleep time at the beginning sleep for five consecutive days. The nights will be monitored by polysomnography.

Sponsors

Associação Fundo de Incentivo à Pesquisa
CollaboratorOTHER
Fundação de Amparo à Pesquisa do Estado de São Paulo
CollaboratorOTHER_GOV
Federal University of São Paulo
Lead SponsorOTHER

Study design

Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
MALE
Age
20 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Body Mass Index ≤ 25 kg/m2 * Physically active individuals * 8 years of school education.

Exclusion criteria

* High level of anxiety - State-Trait Anxiety Inventory (STAI-T) ≥ 35 * High level of anxiety - Beck Depression Inventory ≥ 19 * PSQI - Pittsburgh Sleep Quality Index ≥ 11 * ESS - Epworth Sleepiness Scale ≥ 15 * Irregular rhythm of sleep identified by actigraphy * Sleep disturbance by polysomnography * Shift worker or nocturnal worker; * Obesity; * Smoker; * Alcohol Intake of more than 3 drinks per day; * Taking sleep medications or illicit drugs.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026