Coronary Artery Disease
Conditions
Brief summary
It is the aim of the study to compare the effects of 6 weeks of either high-intensity interval training (HIT; carried out at correctly assessed 85-95% of maximal heart rate), pyramid, or continuous endurance training, on changes of physical exercise capacity in cardiac patients. The three exercise arms (isocaloric) are composed as follows: Endurance training (n=15): 31min at 65-75% HRmax; HIT (n=15): 4x4min intervals at 85-95% HRmax divided by 3x3min of active recovery at 60-70% HRmax, making it a total of 25min; Pyramids (n=15): One Pyramid consists of 8 one-minute blocks. Those are grouped starting with one block of 70-75% HRmax, followed by one block at 75-80% HRmax and another one at 80-85% HRmax. The top of the pyramid are 2 blocks of 85-90% HRmax. Intensity is lowered afterwards with one block at 80-85% HRmax, followed by one block at 75-80% HRmax and last one at 70-75% HRmax. Two more pyramids follow, each divided by 2min of active recovery at 65-70% HRmax, making it a total of 28min. All protocols are initiated by 5min of warm-up and end with 5min of cool-down, both at 60-70% HRpeak. Primary Outcome: Individual maximum power output in watt (Pmax). Secondary Outcome: Change of power output in watt at lactate thresholds at 2 and 4 mmol/l.
Interventions
OTHEREndurance training with constant work load
Endurance training with constant work load(n=15): 31min at 65-75% HRmax
OTHERPyramid-Training
Pyramid-Training (n=15): One Pyramid consists of 8 one-minute blocks. Those are grouped starting with one block of 70-75% HRmax, followed by one block at 75-80% HRmax and another one at 80-85% HRmax. The top of the pyramid are 2 blocks of 85-90% HRmax. Intensity is lowered afterwards with one block at 80-85% HRmax, followed by one block at 75-80% HRmax and last one at 70-75% HRmax. Two more pyramids follow, each divided by 2min of active recovery at 65-70% HRmax, making it a total of 28min.
OTHERHigh-intensity interval training
HIT (n=15): 4x4min intervals at 85-95% HRmax divided by 3x3min of active recovery at 60-70% HRmax, making it a total of 25min
Sponsors
Paracelsus Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
At least one of the following diagnoses within the previous 3 months: * acute coronary syndrome (STEMI) * acute coronary syndrome (NSTEMI) * aortocoronary bypass surgery * PCI * stable coronary heart disease
Exclusion criteria
* Unstable angina pectoris * Heart failure (NYHA IV) * Acute endomyocarditis or other acute infections * Pulmonary artery embolism or phlebothrombosis within the previous 6 months * Hemodynamically unstable arrhythmia * Hypertrophic cardiomyopathy * participation in another study within the previous 6 months * Medical conditions which prevent patients from complying with the exercise program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Individual maximum power output in watt (Pmax) | 6 weeks | Change of individual maximum power output in watt (Pmax) on a bicycle ergometer after the training intervention of controlled physical activity within 6 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Power output in watt at lactate threshold of 2 and 4 mmol/l | 6 weeks | Change of power output in watt at lactate thresholds at 2 and 4 mmol/l |
Countries
Austria
Outcome results
None listed