The Predictive Scores for Gastric Cancer in Gastric Intestinal Metaplasia (GIM) Patient: a Recommendation for Thai Population

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01490541

Enrollment

280

Registered

2011-12-13

Start date

2011-10-31

Completion date

2017-10-31

Last updated

2012-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Intestinal Metaplasia

Keywords

Gastric intestinal metaplasia

Brief summary

The predictive scores for gastric cancer in gastric intestinal metaplasia(GIM) patient: a recommendation for Thai population. Objective: To evaluate major risk factors for gastric cancer in gastric intestinal metaplasia(GIM) patient in order to propose the appropriate recommendation for Thai people. Research Design: Single center, retrospective-cohort study.

Detailed description

Study population and Sample size at Faculty of Medicine, Chulalongkorn University The patients who were diagnosed gastric intestinal metaplasia from 1997 to 2012 and then follow up for 5 years. Estimate sample size =280 * Investigational product, dosage & route of administration * Questionnaire for explore the risk factors * EGD with biopsy * Blood sampling for gastro panel * Duration of participation * 5 years or until diagnose gastric cancer Statistical method: Unconditional-binary-logistic regression

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. All patients were diagnosed GIM 2. All patients have to sign the consent form

Exclusion criteria

1. Previous gastric surgery including gastrectomy and bypass surgery 2. Bleeding tendency including decompensated cirrhosis, chronic kidney disease and long-tem antiplatelets or anticoagulants 3. HIV infection 4. History of proton pump inhibitor use within 1 week 5. History of antibiotic use within 4 weeks

Design outcomes

Primary

Measure	Time frame	Description
The prevalence of early gastric cancer in gastric intestinal metaplasia(GIM) patient from 5 year-follow-up in Thai population	Up to 5 years	In Thailand, gastric cancer patients usually presented with advance stage and carried the dismal prognosis. GIM is a well known precancerous lesion. The appropriate follow-up period in high risk GIM patient can increase the prevalence of early gastric cancer and reduce the mortality rate of gastric cancer

Countries

Thailand

Contacts

Primary ContactRapat Pittayanon, MD

Rapat125@gmail.com66813132112

Backup ContactNuttaphat Namjud, M.Sc.

ampere_nut@hotmail.com66894971957

Outcome results