Embryo Viability
Conditions
Keywords
non-invasive,, metabolomics,, morphology,, embryo selection,, implantation rates
Brief summary
Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The investigators intended to investigate if embryo assessment using non-invasive metabolomic profiling leads to increased implantation rates compared to routine morphology evaluation alone.
Detailed description
Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The aim of the present study was to determine whether embryo selection using non-invasive metabolomic profiling as an adjunct to morphology leads to increased implantation rates compared to routine morphology evaluation alone.
Interventions
PROCEDUREnon-invasive metabolomic profiling
non-invasive metabolomic profiling of IVF human embryos
OTHERmorphological evaluation
Simple microscopic observation of embryos and evaluation of morphological characteristics
Sponsors
Eugonia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 49 Years
Healthy volunteers
Yes
Inclusion criteria
* patients with at least 4 fertilized oocytes
Exclusion criteria
* patients with less that 4 fertilized oocytes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Implantation rates | 6 weeks of pregnancy | To compare non-invasive metabolomic profiling and the traditional method of morphology assessment for embryo selection in terms of implantation and pregnancy rates in a clinical IVF program. |
Countries
Greece
Outcome results
None listed