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The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01488240
Enrollment
6
Registered
2011-12-08
Start date
2012-11-01
Completion date
2028-06-01
Last updated
2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn Scar

Keywords

burn, scar, laser

Brief summary

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

Detailed description

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars. Objectives: To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

Interventions

PROCEDUREpulsed dye laser

laser energy

Sponsors

University of Manitoba
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* burn scar * living in Winnipeg * scar age one to 6 months * Fitzpatrick I-III skin type

Exclusion criteria

* open wound * active infection * previous scar treatment with steroid injection or interferon * established disposition towards keloid scarring

Design outcomes

Primary

MeasureTime frameDescription
Scar Characteristicssix monthsExamine characteristics of scar

Countries

Canada

Contacts

CONTACTJustin P Gawaziuk, MSc
jgawaziuk@hsc.mb.ca2047873669
PRINCIPAL_INVESTIGATORS Logsetty, MD

University of Manitoba

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026