Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma With Similar Structural Optic Nerve Damage

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01488032

Enrollment

Registered

2011-12-08

Start date

2011-03-31

Completion date

2011-11-30

Last updated

2011-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Tension Glaucoma, Normal Tension Glaucoma

Brief summary

The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

Detailed description

It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* persons over 18 years * men or women * with normal- and high-tension glaucoma

Exclusion criteria

* cataract * cloudy cornea and other conditions with bad visualisation quality of optic nerve head * optic nerve atrophy except glaucomatous

Design outcomes

Primary

Measure	Time frame	Description
RNFL in different segments	up to 9 Months	RNFL in upper, lower, temporal and nasal segments

Outcome results