Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01486693

Enrollment

Registered

2011-12-06

Start date

2011-10-31

Completion date

2012-09-30

Last updated

2011-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Uveitis

Keywords

cytomegalovirus, uveitis

Brief summary

The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in Cytomegalovirus (CMV) anterior uveitis.

Detailed description

The investigators will enroll 60 patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping from January 2006 to June 2011. All the patients (40 men, 20 women) were immunocompetent and diagnosed as symptomatic CMV infection. Their medical records will be reviewed, including demographic data as well as their ophthalmic and medical histories. The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in CMV anterior uveitis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping. All the patients were immunocompetent and diagnosed as symptomatic CMV infection.

Exclusion criteria

* Patients without positive results of the CMV PCR * Immunocompromised patients with positive results of the CMV PCR

Design outcomes

Primary

Measure	Time frame	Description
Anterior chamber inflammation	4 weeks after starting treatment	anterior chamber cell grading based on slit lamp microscopy

Secondary

Measure	Time frame	Description
probability of relapse-free	2 years after treatment	Kaplan-Meier curve of relapse-free probability

Countries

Taiwan

Contacts

Primary ContactI-Jong Wang, M.D. PhD

ijong@ntu.edu.tw886-23123456

Outcome results