Death, Liver Disease, Pulmonary Embolism, Thrombophilia
Conditions
Keywords
Liver disease, Pulmonary embolism, Thrombophilia, Death
Brief summary
Major surgery is associated with a postoperative hypercoagulable state related to the surgical trauma that may lead to thromboembolic complications. To the investigators knowledge, only two series have reported the risk of PE after liver surgery with an incidence of up to 6.3% The purpose of this study is to identify the independent risk factors associated with the development of PE after elective liver surgery.
Interventions
PROCEDURELiver resection
Hepatectomy including both minor and major.
RADIATIONComputed Tomography
Computed Tomography +/- pulmonary angiography
Sponsors
Beaujon Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>18 years * Malignant liver diseases * Benign liver diseases
Exclusion criteria
* Age \<18 years * Previous history of thromboembolic events * Living Donor hepatectomies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pulmonary embolism | up to January 2012 | Blood clots in the lungs that may lead to sudden death. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complications | up to January 2012 | Any type of post-operative complications graded according to the Clavien-Dindo Classification of Surgical Complications |
| Length of hospital stay | up to January 2012 | The duration of hospitalization in days. |
| Mortality | up to January 2012 | Post-operative 90-Day Mortality |
Countries
France
Outcome results
None listed