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Surgical Approach for Primary Hyperparathyroidism in the Elderly

Surgical Approach for Primary Hyperparathyroidism in the Elderly - a Prospective Study

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01484379
Enrollment
0
Registered
2011-12-02
Start date
2011-12-31
Completion date
2015-11-30
Last updated
2017-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multigland Disease in Primary Hyperparathyroidism

Keywords

Primary Hyperparathyroidism, multigland disease, neck exploration, elderly

Brief summary

Following a personal observation and a retrospective analysis of the data, the investigators hypothesise that there is increased frequency of multiple gland disease in primary hyperparathyroidism in the elderly. This study will include patients over the age of 65, diagnosed with primary hyperaprathyroidism, referred for surgery and suspected to have a single adenoma according to preoperative imaging. Surgery will begin with a focal parathyroid exploration as suspected followed by an exploration of the other gland at the same time. Data will be analysed to determine the frequency of multigland disease in this population.

Interventions

PROCEDUREunilateral neck exploration

All elderly patients with primary hyperparathyroidism suspected to have a single gland disease will have a unilateral neck exploration following the index gland identification.

Sponsors

Rambam Health Care Campus
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patient with primary hyperparathyroidism. * patients with an indication for surgery. * Suspected adenoma on preop images. * minimum age of 65.

Exclusion criteria

* patients younger than 65. * cases where imaging didn't locate any adenoma. * patients who did not consent to participate in the study.

Design outcomes

Primary

MeasureTime frame
Frequency of multigland disease in hyperparathyroidism in the elderly.two years

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026