Lung Adenocarcinoma
Conditions
Keywords
lung adenocarcinoma, prognosis, tumor aggressiveness, imaging biomarker, genetic biomarker
Brief summary
to determine the values of imaging and genetic biomarkers for prediction of tumor aggressiveness and prognosis in patient with early stage lung adenocarcinoma to Identify unique copy number alteration in patient with early stage lung adenocarcinoma to evaluate the long-term change of ground-glass nodule combined with lung adenocarcinoma to suggest a guideline for planning an appropriate follow-up examination and management
Interventions
OTHERCT, PET, copy number alteration
Duel-energy CT, PET, copy number alteration
Sponsors
Korean Foundation for Cancer Research
Samsung Medical Center
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* A. Clinically and radiologically suspected lung adenocarcinoma * B. Newly-diagnosed Stage I or II from the clinical work up including PET/CT * C. Performance status of 0 to 1 on the ECOG scale * D. Age 20 years or older * E. Able to tolerable DECT imaging required by protocol * F. Able to give study-specific informed consent
Exclusion criteria
* A. Prior malignancy * B. planning of Definitive RTx 나 neoadjuvant CCRTx * C. Poor cardiopulmonary reserve
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prediction of tumor aggressiveness | five years |
Secondary
| Measure | Time frame |
|---|---|
| prognosis of early stage lung adenocarcinoma following operation | five years |
Countries
South Korea
Contacts
Primary ContactYoung Mog Shim, Dr.
Backup ContactHo Yun Lee, Dr.
Outcome results
None listed