Feasibility of Mutational Analysis of Non-Small Cell Lung Cancer (NSCLC) Using Low-volume Lung Aspirates

Feasibility of Gene Expression Profiling Using Low-volume Lung Aspirate

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01482572

Enrollment

Registered

2011-11-30

Start date

2012-01-31

Completion date

2015-11-30

Last updated

2015-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Keywords

biopsy, needle aspiration, mutational analysis

Brief summary

The purpose of this study is to evaluate the feasibility of aspiration samples for mutational analysis in patients with a non-small cell lung cancer (NSCLC).

Detailed description

The investigators will compare results of mutational analysis from a core needle biopsy and fine needle aspiration.

Interventions

PROCEDUREbiopsy

percutaneous lung biopsy and aspiration

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* primary tumor or a metastatic lung lesion requested for mutational analysis

Exclusion criteria

* a) lesions located adjacent to the large central bronchi or vessels * b) peribronchovascular lesions with prominent internal CT air-bronchograms, which were considered difficult to be avoided by needle pass * c) lesions in patient with severe respiratory compromise

Design outcomes

Primary

Measure	Time frame
Success rates for mutation analysis	one year

Secondary

Measure	Time frame
Technical success rate of biopsy procedure	one year

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026