Cutaneous Malignant Melanoma
Conditions
Brief summary
Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). This study will be an exploratory analysis by miRNA expression profiling using microarrays.
Detailed description
Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cutaneous malignant melanoma metastases (CMMM) and benign melanocytic naevi (BMN) is limited. Patients with PCMM, CMMM and BMN are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).
Interventions
PROCEDUREBiopsy
Biopsy
Sponsors
Ruhr University of Bochum
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Primary Cutaneous Malignant Melanoma * Cutaneous Malignant Melanoma Metastases * Benign Melanocytic Naevi
Exclusion criteria
\- Other Skin Cancer than Primary Cutaneous Malignant Melanoma
Countries
Germany
Outcome results
None listed