Dehydration, Diarrhea
Conditions
Keywords
Dehydration, Hydration, Muscle composition, Diarrhea, Pediatrics, Neonatology, Ultrasound
Brief summary
Study will verify ability of infant Hydration Monitor (IHM) to assess changes of hydration status in newborns and infants by means of ultrasound velocity measurements through muscle tissues. Changes of tissue hydration will be followed during first days of life in newborns and in acute diarrhea in small children during re-hydration therapy. Weighting and clinical dehydration symptoms will be used as controls.
Interventions
None listed
Sponsors
Bill and Melinda Gates Foundation
Artann Laboratories
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 3 Years
Healthy volunteers
Yes
Inclusion criteria
* Newborns from 1 to 7 days old, * Health infants from 1 month to 3 years old, * Any ethnicity, * Male or female, * Infants with diarrhea, * Acute gastroenteritis, * Diarrhea and/or vomiting, * Suspected dehydration
Exclusion criteria
* Congenital heart disease, * Renal failure, * Chronic liver disease, * Chronic lung disease, * Inflammatory bowel disease, * Immune deficiency, * Severe malnutrition, * Any external damage to skin of leg, * Infants and Children whose parents refuse permission to be included
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assess the ability of IHM to measure changes of hydration status ni newborn and infants | 1 week to several months | Infants and small children diagnosed with diarrhea or presenting to the hopsital with diseases known to cause dehydration are eligible |
Countries
Latvia
Outcome results
None listed