Effect of Body Composition and Metabolism on Oocyte Gene Expression

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01480024

Enrollment

Registered

2011-11-28

Start date

2011-04-30

Completion date

2019-05-02

Last updated

2023-12-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

healthy women, oocytes, in vitro fertilization, pregnancy, childbearing-age

Brief summary

The investigators will test the hypothesis that obese women have a unique oocyte gene expression profile that differs significantly from that of normal weight women.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 38 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI \< 25 (N=35) or BMI ≥ 30 (N=35) * Seeking fertility treatment at the Arkansas Fertility and Gynecology Associates Clinic * Assisted reproduction will include the oocyte retrieval technique * 18 to 38 years of age

Exclusion criteria

* Any health condition or medication that may interfere with the study outcome as determined by the investigators

Design outcomes

Primary

Measure	Time frame
oocyte gene expression profile	1-2 weeks

Countries

United States

Outcome results