Prospective Dengue Seroprevalence Study in 5 to 10 Year-old Children

Prospective Dengue Seroprevalence Study in 5 to 10 Year-old Children in India

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01477671

Enrollment

667

Registered

2011-11-22

Start date

2011-09-30

Completion date

2013-12-31

Last updated

2018-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dengue, Dengue Fever, Dengue Hemorrhagic Fever

Keywords

Dengue, Dengue Fever, Dengue Hemorrhagic Fever

Brief summary

This is a descriptive prospective community-based seroprevalence study. Primary objective: * To determine the prevalence of specific antibodies (immunoglobulin G \[IgG\]) against dengue in healthy 5 to 10 year-old children in India. Secondary objectives: * To determine the dengue virus serotype (DeNV-1,2,3 and /or 4) specific to the antibodies in positive (IgG) samples * To estimate the prevalence of specific antibodies (IgG) against Japanese encephalitis in healthy 5 to 10 year-old children in India.

Interventions

None listed

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

5 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* Aged between 5 and 10 year-old on the day of inclusion * Healthy child as reported by the parent or legally qualified guardian * Being registered in selected study site * Provision of the informed consent form signed by at least one parent or legally qualified guardian * For children between 8 and 10 years old, provision of the assent form signed.

Exclusion criteria

* N/A

Design outcomes

Primary

Measure	Time frame
Prevalence of positive samples with dengue specific serotype DENV 1, 2,3 and/or 4	Baseline

Secondary

Measure	Time frame
Prevalence of positive serum samples with JEV specific IgG antibodies	Baseline

Countries

India

Outcome results