Arthritis Research UK Gout Treatment Trial - Phase 2

Conditions

Gout

Brief summary

The purpose of this study is to determine in community-derived patients with gout the effectiveness, and cost effectiveness, of a nurse-led complex intervention that reflects recommended best practice (including patient information concerning gout, its prognosis and its non-pharmacological and drug options).

Stamp LK, Frampton C, Morillon MB, Taylor WJ, Dalbeth N, Singh JA, Doherty M, Zhang W, Richardson H, Sarmanova A, Christensen R.

2021-11-0537 citations

10.1016/s2665-9913(21)00319-2

Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial.

Doherty M, Jenkins W, Richardson H, Sarmanova A, Abhishek A, Ashton D, Barclay C, Doherty S, Duley L, Hatton R, Rees F, Stevenson M, Zhang W.

2018-10-01228 citations

10.1016/s0140-6736(18)32158-5

Interventions

OTHERNurse intervention

Complex package of care involving patient information and advice concerning lifestyle modification and recommended drug therapy.

OTHERStandard care

Continuing standard General Practitioner led care.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* Diagnosis of gout * At least one acute attack of gout within previous 12 months

Exclusion criteria

\- Inability to give informed consent and known terminal or mental illness

Design outcomes

Primary

Measure	Time frame
Reduction in serum uric acid levels	2 years

Secondary

Measure	Time frame
Reduction in number of self reported acute attacks during year 2	2 years
Improved Quality of Life scores at study end	2 years

Countries

United Kingdom

Outcome results

None listed