Pregnancy Outcomes in Congenital Myasthenie Syndrome

Retrospective Study :Describe the Changes of the Disease in Many Cases Likely to Aggravate.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01474980

Acronym

POCoMS

Enrollment

Registered

2011-11-18

Start date

2010-01-31

Completion date

2011-10-31

Last updated

2011-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Myasthenic Syndrome

Keywords

Congenital Myasthenic Syndrome, Pregnancy, Outcome

Brief summary

This is a retrospective study that follows the clinical evolution, the pregnancy and the post-partum perioad of female patients with Congenital Myasthenic Syndrome.

Detailed description

The aim of this study is to better understand the action of hormonal factors that are presumably incriminated for the fluctuation of the disease. The investigators would also like to better adress the issues of women with Congenital Myasthenic Syndrome, who desire a pregnancy : the possibility of decompensation, the problems that can arise during the course of the childbearing, the risk of foetal malformations.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult women * Congenital myastenic syndrome genetically confirmed or with clinical compatible and electrophysiological evidence * Written consent

Exclusion criteria

* Neurological or general pathology occurs significantly with the initiation and conduct of a pregnancy.

Outcome results