Obstipation
Conditions
Brief summary
Coffee might stimulate bowel movement and thus overcome obstipation in intensive care unit (ICU) patients.
Detailed description
Critically ill patients requiring ventilator support frequently suffer from obstipation. We hypothesize that coffee, administered either orally or rectally, might stimulate bowel movement.
Interventions
DIETARY_SUPPLEMENTcoffee
patients will receive a cup of coffee at room temperature orally twice daily
DIETARY_SUPPLEMENTcoffee rectally
patients receive an enema of two cups of coffee at room temperature once daily
Sponsors
University Hospital Heidelberg
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* admission to the medical intensive care unit of the Dept. of Gastroenterology at the university hospital heidelberg * requires ventilator support for an anticipated more than 72 hours * age older than 18 years
Exclusion criteria
* pregnancy * known allergy to coffee * mechanical ileus * presence of enterostoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel movement rate | participants will be followed for the duration of hospital stay, an expected average of 5 weeks |
Secondary
| Measure | Time frame |
|---|---|
| time on mechanical ventilation | participants will be followed for the duration of intensive care unit stay, an expected average of 3 weeks |
| time of stay on ICU | participants will be followed for the duration of hospital stay, an expected average of 5 weeks |
| lengths of hospitalisation | an average of 5 weeks of hospital stay is expected |
| in hospital mortality | participants will be followed for the duration of hospital stay, an expected average of 5 weeks |
| long term mortality | 6 months following discharge |
Countries
Germany
Outcome results
None listed