Coronary Artery Disease
Conditions
Keywords
drug-eluting coronary stent, percutaneous coronary intervention
Brief summary
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
Detailed description
A group of 814 consecutive patients undergoing percutaneous coronary intervention (PCI) was enrolled between 2007 and 2010, of which 527 were treated with EES and 287 with BES implantation. Clinical outcome was compared in 200 pairs using propensity score matching. The primary endpoint was a composite of death, myocardial infarction (MI) and target vessel revascularisation (TVR) at two-year follow-up.
Interventions
None listed
Sponsors
University of Freiburg
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 120 Years
Healthy volunteers
No
Inclusion criteria
* all patients with at least one BES or EES for de novo stenosis
Exclusion criteria
* patients with at least one non-study stent * patients with both study stent * patients with life expectancy \< 3 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Composite of Death, Myocardial Infarction and Target Vessel Revascularization | up to 24 months | The primary outcome is the above mentioned composite of adverse events in order to measure their cumulative incidence (i.e. the rate of occurrence of such events in the study population over a predefined time periode). |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular death | up to 24 months |
| Any Revascularization | up to 24 months |
Countries
Switzerland
Outcome results
None listed