Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01468402

Enrollment

Registered

2011-11-09

Start date

2008-09-30

Completion date

2009-08-31

Last updated

2011-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exposure to Magnetic Field, Uterine Leiomyoma

Keywords

Leiomyoma, uterine artery embolization, magnetic resonance imaging

Brief summary

The purpose of this study is to determine predictive factors in the pelvic magnetic resonance in the response of arterial embolization of uterine leiomyoma.

Detailed description

This study followed symptomatic premenopausal women with uterine leiomyoma who underwent uterine artery embolization (UAE). Treatment was accompanied by magnetic resonance imaging of both the volume of the entire uterus and the leiomyomas one month before and six months after UAE. This patients were treated at the Uterine Leiomyoma Sector of the Department of Obstetrics and Gynecology, Medicine College of the University of São Paulo. In this study, the investigators examined 179 leiomyomas in 50 patients.

Interventions

PROCEDUREMagnetic Resonance Image

The leiomyomas were evaluated individually. MR was used to evaluate morphology: the radiological dimension(s) of the leiomyoma and uterus and the volume. The number of leiomyoma fibroids was determined, and their location in the myometrium. Perfusion and the characterization of the T2 signal were also evaluated.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* ultrasound diagnosis of uterine leiomyoma * presence of symptoms (menorrhalgia and/or pelvic pain) * indication for UAE(the desire to keep the uterus and/or contraindications for surgery).

Exclusion criteria

* malignant genital neoplasms * pelvic inflammatory disease * allergy to iodinated contrast * coagulopathy, renal failure * vasculitis * pelvic irradiation * pregnancy * subserosal leiomyoma with a pedicle smaller than 50% of diameter of the fibroid.

Design outcomes

Primary

Measure	Time frame	Description
Leiomyoma reduction in patients who underwent uterine artery embolization	One month before(baseline) and six month after the embolization	Use the magnetic resonanse to evaluate factors that predicted leiomyoma reduction in patients who underwent uterine artery embolization

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026