Laser Iridotomy Versus Surgical Iridectomy in Early Angle Closure

Laser Peripheral Iridotomy Versus Surgical Peripheral Iridectomy in Early Angle Closure:a Randomized Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01468103

Enrollment

120

Registered

2011-11-09

Start date

2009-08-31

Completion date

2012-08-31

Last updated

2011-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Pressure Changes, Peripheral Anterior Synechiae Increasing

Keywords

intraocular pressure, Peripheral anterior synechiae

Brief summary

This is a randomized controlled clinical trial to compare laser peripheral iridotomy(LPI) and surgical peripheral iridectomy. Subjects of primary angle closure suspect, primary angle closure will be randomized to undergo LPI or SPI. Subjects are proposed to be followed up for 3 years.

Detailed description

The following will be studied: 1. To evaluate the safety of these two techniques for the treatment of angle closure. 2. To compare the anterior chamber reaction and IOP changes post surgery. 3. TO establish the UBM/ASOCT chamber angle parameters changes pre and post surgery. 4. To assess the development of PAS.

Interventions

PROCEDURESurgical Iridectomy

Surgical Iridectomy is now widely used in our clinical.

PROCEDURELaser Iridotomy

alternative choice to surgical iridectomy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. more than 50 years old 2. Diagnosis of either: Primary angle closure suspects, Primary angle closure in need of laser iridotomy or surgical iridectomy 3. Able to give Informed concent

Exclusion criteria

1. Ophthalmic diseases other than glaucoma and cataract 2. pseudophakic or aphakic patients 3. inability to attend regular follow-up assessment or to give informed written consent 4. Secondary causes of angle closure e.g. subluxed lens, uveitis, trauma and neovascular glaucoma 5. Participating in another study 6. monocular patients

Design outcomes

Primary

Measure	Time frame
intraocular pressure	3 years

Secondary

Measure	Time frame	Description
Angle assessment parameters	3 years	Angle assessment parameters,such as anterior chamber openning distance,are acquired by anterior segment optical coherence tomography.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026