Pain, Postoperative
Conditions
Brief summary
In this study the investigators wish to compare the effect of a selective axillary nerve block to placebo in patients undergoing arthroscopic shoulder surgery. It is the investigators hypothesis that the amount of morphine consumption in the first 4 hours postoperatively in the intervention group will be significant lower than in the placebo group.
Interventions
DRUGropivacaine
Single shot nerve block with ropivacaine 10-20 ml; 7,5 mg/ml
DRUGSodium chloride
Single shot nerve block with isotonic sodiumchloride 10-20 ml; 0.9%
Sponsors
Hillerod Hospital, Denmark
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Subjects undergoing arthroscopic shoulder surgery * Age between 18 and 80 years * ASA 1-3 * BMI between 18 and 35 kg/m2 * Subjects which have given their written informed consent
Exclusion criteria
* Subjects unable to cooperate to the investigation * Subjects not understanding or speaking danish * Subjects allergic to intervention drugs * Daily use of strong analgesics (morphine, oxycontine, ketogan) * Alcohol or medicine misuse * Failure of nerve block
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Morphine consumption | 0-4 hours postoperatively | Patients are coupled to an intravenous PCA pump. The amount of morphine administered by the patient in the first 4 hours postoperatively is registered. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale (VAS) score | 0-12 hours and 12-24 hours postoperatively | Postoperative VAS scores during the first 24 hours postoperatively, divided into two periods. |
| Total morphine consumption | 0-24 hours postoperatively | The total amount of morphine administered during the first 24 hours postoperatively |
| Postoperative nausea and vomiting (PONV) | 0-4, 0-12 and 12-24 hours postoperatively | Postoperative nausea evaluated on a 1-3 scale with and without vomiting |
| Escape block | 0-4 hours postoperatively | The use of an escape block (interscalene brachial plexus block) in patients with pain breakthrough despite IV morphine 0-4 hours postoperatively. |
| Bolus morphine 5 mg iv | 0-4 hours postoperatively | Number of morphine boli administered during the first 4 hours postoperatively |
Countries
Denmark
Outcome results
None listed