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Autonomic Nervous System, Fatigue and Intolerance to Physical Training, and Overtraining in High-Level Athletes

Autonomic Nervous System, Fatigue and Intolerance to Physical Training, and Overtraining in High-Level Athletes. A Multicentre Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01463761
Enrollment
131
Registered
2011-11-02
Start date
2010-07-31
Completion date
2012-12-31
Last updated
2013-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Athletes, Fatigue, Training

Keywords

High-level athlete, ANS activity, Overtraining

Brief summary

Sports training aims to enhance an athlete's performance (overcompensation). To do that, the athlete must go through periods of fatigue and lower performance (overreaching). When the training plan is balanced, this fatigue is short and reversible.If the training load is too heavy or if recuperation periods are too short, it can lead to persistence fatigue that may only be reversible in the long term. This state of fatigue is part of the broader clinical picture of overtraining, which includes stark changes in performance as well as mood and sleep disorders. Many prediction and characterization methods based on biological markers have been evaluated, but they have not been put into practice in sports training due to obstacles such as reliability, interindividual variability and high costs. This study aims to evaluate a new approach based on the variability of an individual's heart rate (RR variability), which is a way of measuring autonomic nervous system (ASN) activity. It is non-invasive, low-cost, and has already proven useful in athlete health monitoring.

Detailed description

The investigators propose to describe the variation of these ANS regulation factors over a full year, in a population of high-level athletes, in order to measure changes in regulation which may be predictive of potential fatigue and intolerance to physical training, if such a syndrome came to be observed among the study group.

Interventions

DEVICEANS activity

This ANS activity is measured by nocturnal heart rates records with Holter ECG.

Sponsors

Minister of Youth Affairs and Sports, France
CollaboratorOTHER_GOV
Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
14 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* High-level athlete, enrolled in a Ministry-recognized Pôle * Participant signed the informed consent form

Exclusion criteria

* Confirmed current overtraining syndrome * Known pregnancy on inclusion * Athlete using cardio-inhibitor or cardio-accelerator drugs

Design outcomes

Primary

MeasureTime frameDescription
Autonomic nervous system (ANS) activityOne yearThis ANS is mesured during the night using a spectral analysis of nocturnal heart rate variability.
Fatigue and physical trainingOne yearFatigue and physical training potetially due to overtraining, suspected based on a very significant, long-term worsening in performance

Secondary

MeasureTime frameDescription
French Society of Sports Medicine questionnaireEvery 15 days (from inclusion to one year)The questionnaire was designed to detect early signs of overtraining. It includes 54 yes/no questions. Subjects who answer yes to more than 20 questions are considered at risk for overtraining.
kinetic of the ANS activityEvery 15 days (from the iclusion to one year)ANS is mesured during the night using a spectral analysis of nocturnal heart rate variability
Sleep quality questionnaireEvery 3 months (from inclusion to one year)The questionnaire is self-administered. It includes two parts. The first part consists of several questions regarding sleep during the previous night. The second part aims to evaluate the physical exertion load during the previous day's training session(s). Participants will fill one questionnaire/day for a whole week. Each questionnaire period must coincide with a training period (interseason, volume, intensity, or competition.)
POMS (Profile of Mood States) questionnaireEvery 3 months (from inclusion to inclusion)
orthostasis testEvery 15 days (from inclusion to one year)ANS activity measurements (RR variability) during active orthostasis transition on waking up in the morning

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026