Transcranial Direct-Current Stimulation in Childhood Dystonia

Pilot Open-label and Blinded Clinical Trial of Transcranial Direct-current Stimulation in Childhood Dystonia

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01460771

Enrollment

100

Registered

2011-10-27

Start date

2011-09-30

Completion date

2017-09-30

Last updated

2014-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood Onset Dystonias

Keywords

childhood dystonia

Brief summary

The investigators hypothesize that transcranial direct current stimulation over the motor cortex will reduce muscle overflow and improve hand function in children with primary or secondary dystonia.

Interventions

DEVICETDCS (Transcranial Direct-current Stimulation)

active TDCS

DEVICEsham TDCS (Transcranial Direct-current Stimulation)

TDCS at 0mA

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

4 Years to 21 Years

Healthy volunteers

Inclusion criteria

* dystonia affecting one or both hands * age 4 to 21 years

Exclusion criteria

* metal implants in the head * inability to cooperate with instructions

Design outcomes

Primary

Measure	Time frame	Description
Hand muscle overflow	10 minutes post- transcranial Direct-current Stimulation (TDCS)	surface EMG measure of overflow into muscles during attempted relaxation.

Countries

United States

Contacts

Primary ContactAprille Tongol

tongol@usc.edu213-740-1317

Backup ContactDiana Ferman

dferman@usc.edu310-425-2342

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026