Deep Venous Thrombosis, Pulmonary Embolism
Conditions
Brief summary
The primary objective of this study was to estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically. The secondary objectives were to assess the association between PE and DVT, to identify risk factors for VTE, and to determine the outcome of VTE.
Detailed description
Background: Pulmonary embolism (PE) produces nonspecific or minimal symptoms in mechanically ventilated (MV) patients, leading to underdiagnosis. We estimated the prevalence of PE and associations with deep vein thrombosis (DVT) among MV patients. Methods: Consecutive MV patients who required thoracic computed tomography (CT) in a single ICU. Compression ultrasound of the four limbs was performed within 48 hours of inclusion. Curative anticoagulation therapy was given immediately after PE diagnosis.
Interventions
None listed
Sponsors
University Hospital, Grenoble
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all patients requiring invasive MV and thoracic contrast-enhanced CT for any reason
Exclusion criteria
* a diagnosis of PE before ICU admission, * allergy to contrast agents, * and age younger than 18 years.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Find a pulmonary embolism on the CT scan | CT scan at the day of inclusion | TO estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically. |
Secondary
| Measure | Time frame |
|---|---|
| To find thrombus on compression ultrasound (CUS) of the four limbs | CUS within 48 hours after the CT scan |
Countries
France
Outcome results
None listed