Comparison of Four Different Recruitment Maneuvers in Patients After Coronary Surgery

Comparison of Different Types of Postoperative Pulmonary Recruitment and Predicting Its Efficacy Following Off-pump Coronary Artery Bypass Grafting

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01457651

Acronym

RECR-CABG

Enrollment

Registered

2011-10-24

Start date

2010-03-31

Completion date

2012-01-31

Last updated

2013-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia, Recruitment

Keywords

Recruitment, Coronary artery bypass grafting, Postoperative period

Brief summary

The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism. The investigators compare three different types of alveolar recruitment in patient after cardiac surgery, to reveal which one is better.

Detailed description

The study compares three different approaches to alveolar recruitment maneuvers in the immediate postoperative period after off-pump coronary bypass grafting.

Interventions

PROCEDUREAlveolar recruitment

Four approaches: 1. CPAP 40 cm H2O 2. Peak pressure 40 cm H2O 3. PEEP 15 cm H2O for 300 sec 4. no intervention (controls)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age between 18 and 75 * Off-pump coronary artery bypass grafting * Possibility to discontinue respiratory support in the first day after intervention

Exclusion criteria

* Signs of ARDS * COPD in decompensation phase * Requirement for inotropic support(epinephrine \>0,1 mcg/kg/hr) * Bronchiectases * Pregnancy * Morbid obesity * Aortic aneurism * AMI in previous month

Design outcomes

Primary

Measure	Time frame	Description
Respiratory support	24 hrs	The duration of the postoperative respiratory support

Secondary

Measure	Time frame	Description
Length of ICU and hospital stay	28 Days	Length of ICU and hospital stay
The incidence of postoperative atelectasis	24 hrs	Incidence of atelectases during 24 hrs
Incidence of reintubation	24 Hrs	—
Oxygenation	12 hrs after extubation	Changes in PaO2/FiO2 ratio

Countries

Russia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026