The Predictors for Continuous Renal Replacement Therapy in Liver Transplant Patient

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01457534

Enrollment

148

Registered

2011-10-24

Start date

2011-01-31

Completion date

2011-02-28

Last updated

2013-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Transplantation

Brief summary

Background. Acute renal failure after liver transplantation (LT) requiring continuous renal replacement therapy (CRRT) adversely affects patient survival. However, there are few reports to assess the predictors for postoperative CRRT in liver transplant patients. The investigators undertook this study to identify perioperative factors that would predict patients at risk of CRRT. Patients and Methods. The investigators retrospectively reviewed the data of 148 liver transplant patients from January 2007 to November 2010 at Severance Hospital, Yonsei University HealthSystem, in Seoul, Korea. The number of patients treated with CRRT was 44 (18 patients from living and 26 from deceased donors) and those without CRRT was 104. Univariate and stepwise logistic multivariate analyses were performed.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Age 19-65 year * Liver transplant patients from January 2008 to December 2011

Exclusion criteria

* Patients treated with CRRT before transplantation

Design outcomes

Primary

Measure	Time frame	Description
status before operation	1 day before operation	laboratory data(ex : total bilirubin, albumin, coagulation factors, blood gas analysis(arterial CO2 pressure. Blood urea nitrate/Creatinine, Hemoglobin/Hematocrit.)
the amount of ascites	intraoperative	—
the duration of anesthesia and operation	intraoperative	—
intraoperative hemodynamic instability	intraoperative	—
intraoperative bleeding	intraoperative	—
Intraoperative urine output	intraoperative	—
the types of donation(living or deceased donor)	intraoperative	—
survival rate	on the postoperative 28th days, 365 days	—
postoperative bleeding amount	on the postoperative 28th days, 365 days.	—
postoperative CRRT(continuous renal replacement therapy),	on the postoperative 28th days, 365days	—
mortality	on the postoperative 28th days, 365 days.	—

Countries

South Korea

Outcome results