Pain Compared Between the First and the Second Surgery in Staged BTKA

Comparison of Postoperative Pain in the First and Second Knee in Staged Bilateral Total Knee Arthroplasty: Clinical Evidence That Central Sensitization Increases Systemic Pain Sensitivity

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01457313

Enrollment

Registered

2011-10-21

Start date

2011-10-31

Completion date

2013-03-31

Last updated

2013-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).

Detailed description

postoperative pain and analgesic consumption is compared between the first and second total knee arthroplasty (TKA) operation.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 85 Years

Healthy volunteers

Inclusion criteria

* patients undergoing elective bilateral staged total knee arthroplasty at a 1-week interval under spinal anesthesia, * age \<=85 * American Society of Anesthesiologists physical status of I to II

Exclusion criteria

any contraindication to spinal anesthesia or femoral nerve block such as coagulopathy; conversion to general anesthesia; preexisting pain syndrome; abnormal liver function or renal test results; severe heart, liver, or renal disease; history of stroke or neurologic deficits; psychiatric disorder; chronic opioid use; drug dependency; allergy to study medications; inflammatory joint disease; previous surgery on or trauma of the knee; difference in preoperative VAS score of ≥ 20 (at rest and at maximum knee flexion) between each side of the knee; body mass index of ≥ 40 kg/m2; and inability to comprehend the VAS or to use patient-controlled analgesia (PCA.

Design outcomes

Primary

Measure	Time frame	Description
VAS	from the end of the TKA surgery until postoperative 48 hour	visual analogue scale

Secondary

Measure	Time frame	Description
analgesic consumption	from the end of the TKA surgery until postoperative 48 hour	patient controlled analgesia (fentanyl)
rescue analgesic	from the end of the TKA surgery until postoperative 48 hour	ketoprofen
antiemetics	from the end of the TKA surgery until postoperative 48 hour	antiemetics total amount

Countries

South Korea

Contacts

Primary ContactMihyun Kim, PhD

snmd56@yahoo.com82-31-787-7499

Outcome results