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Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study

Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01456871
Enrollment
6
Registered
2011-10-21
Start date
2011-08-31
Completion date
2012-03-31
Last updated
2013-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Mechanoreceptors, PIP joint, Ligamento-muscular reflexes

Brief summary

The purpose of the study is to gain a better understanding of mechanoreceptors in the PIP joint ligamento-muscular reflexes and their role is.

Detailed description

Encapsulated nerve endings called mechanoreceptors are end components of afferent nerves and have specialized end organs surrounding the nerve terminal. Those receptors are concentrated in various human periarticular tissues. It is believed that these mechanoreceptors in the periarticular tissues are related to muscle reflexes. However, it is still unknown which type of mechanoreceptors contribute to the muscle reflexes and whether the mechanoreceptors excite and/or inhibit muscle activation. In the investigators previous studies, mechanoreceptors in the human proximal interphalangeal (PIP) joint and surrounding structures have been extensively examined. The investigators have identified that Pacini-like nerve endings in the PIP joint were found in substantial numbers in the junction of the C1 pulley and accessory collateral ligaments. The investigators hypothesize that the Pacini-like nerve endings in the junction of the C1 pulley generate activity in the associated flexor muscle/tendon in the finger.

Interventions

PROCEDUREGuided insertion of electrodes

Fine-wire needle electrodes (30mm x 27gauge needle with a pairs of 0.051mm, insulated, hooked wires, Motion Lab Systems, Baton Rouge, LA) guided by sonographic evaluation of the pulley system using a Philips iU22 Ultrasound Machine (Philips Ultrasound Systems, Bothell, WA), a 17-5 MHz linear array transducer, and standard ultrasound gel.

PROCEDUREElectromyographic (EMG) recording

EMG signal recording, performed with an MA 300 EMG system (Motion Lab Systems, Baton Rouge, LA).

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

\- Females aged 20-30

Exclusion criteria

* A history of any upper extremity injury or disorder in the non-dominant arm * A history of any neurologic or bleeding disorder, or taking blood-thinning medication. * Presence of Linbug-Comstock syndrome

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026