Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01455662

Enrollment

100

Registered

2011-10-20

Start date

2010-01-31

Completion date

2011-12-31

Last updated

2011-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

cardiac arrest

Brief summary

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.

Detailed description

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR). Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p \<0.05).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion criteria

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease. * patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest * less 18 years old

Design outcomes

Primary

Measure	Time frame
mortality	1 year

Secondary

Measure	Time frame
correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance	6 hours

Countries

Brazil

Contacts

Primary ContactVanessa M Oliveira, MD

vanessa.oliveira480@gmail.com05192513723

Backup ContactDiego Riveiro, MD

dmriveiro@yahoo.com.br05184175632

Outcome results