The Effect of Auditory Stimuli on Heart Rate Variability (HRV) Among Patients With Acquired Brain Injury (ABI)

The Effect of Auditory Stimuli on Heart Rate Variability (HRV) During Resting and During Physical Activity Among Patients With Acquired Brain Injury (ABI)

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01454557

Enrollment

Registered

2011-10-19

Start date

2011-11-30

Completion date

Unknown

Last updated

2011-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired Brain Injury

Keywords

Acquired Brain Injury, Heart Rate Variability (HRV), Auditory Stimuli, Physical Activity

Brief summary

Heart Rate Variability (HRV) reflects the responsiveness of the autonomic system to an external stimuli. The aim of this system is to maintain homeostasis.The variability implies on the interaction between the sympathetic and the parasympathetic systems to maintain the ongoing changes of the autonomic system. Following Acquired Brain Injury (ABI), there can be a damage to the Central Nervous System (CNS) function. The damages described in the literature are cognitive, motor and behavioural function, while there is less relation to the autonomic system. The autonomic system can influence the ability of patient with ABI to participate in the rehabilitation program. The aim of this work is to investigate the activity of the autonomic system activity as manifested by HRV among patients with ABI in different conditions: resting, during activity and while listening to different auditory stimuli.

Interventions

OTHERAuditory Stimuli

Auditory Stimuli during rest and during physical activity

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* 2-4 months from acceptance to rehabilitation medical stable

Exclusion criteria

* medical unstable a significant hearing deficit premorbid neurological or mental condition

Design outcomes

Primary

Measure	Time frame	Description
Heart Rate Variability	first measurement: 2 weeks to 2 months from hospitalization to the department: 24 hours EKG follow up for HRV base line. Last measurement: before the release from rehabilitation (up to 12 months).	Heart Rate Variability as measured by HOLTER EKG during the 4 different conditions: first measuerement 2-8 weeks from hospitalization in the TBI rehabilitation department-24 hours detection for HRV baseline. Second measurement: a week after: EKG during the 4 conditions. Third measurement:a month after the first measure, Fourth measurement: 2 months after the first one. Last measurement: Before the release home from rehabilitation (up to one year from the first measurement).

Countries

Israel

Contacts

Primary ContactOfer Keren, MD

ofer.keren@sheba.health.gov.il972-3-5305183

Backup ContactAba Ratner, MD

Aba.Ratner@sheba.health.gov.il972-3-5305183

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026