Comparing 4L Golytely to 2L Golytely With 15mg Bisacodyl Regimens for Inpatient Colonic Preparation

2L Golytely and Oral Bisacodyl 15 mg Versus 4L Golytely Regimen for Inpatient Colonoscopy Bowel Preparation: A Randomized, Non-Inferiority Open Trial

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01452737

Enrollment

Registered

2011-10-17

Start date

2011-11-30

Completion date

2012-05-31

Last updated

2013-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonoscopy

Keywords

colonoscopy, bowel preparation, Golytely

Brief summary

The investigators wish to compare the efficacy and patient tolerability of a preparation consisting of 2L Golytely (PEG + electrolytes) plus 15mg of bisacodyl vs the standard preparation of 4L Golytely. The investigators hypothesize that 2L Golytely with 15mg bisacodyl will show similar bowel cleansing efficacy while offering better tolerability.

Interventions

DRUGStandard Bowel Prep

Subjects will be asked to take 4L of Golytely the day prior to procedure.

DRUG2L Golytely/bisacodyl

Subjects will be asked to take 2L Golytely and 15mg bisacodyl the day prior to procedure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* Inpatients undergoing colonoscopy * Age 19 or over

Exclusion criteria

* Unable to provide informed consent * Patients with constipation * Patients with suspected bowel obstruction or severe inflammatory bowel disease * Same-day colonoscopy * Intensive/critical care patient * History of colorectal resection

Design outcomes

Primary

Measure	Time frame	Description
Difference in Boston Bowel Preparation Scale & Ottawa Bowel Preparation Scale between the two groups	30min	These are established rating scales to evaluate the quality of bowel prep. The ratings will be compared between the two groups.

Secondary

Measure	Time frame	Description
Difference in the number of participants who develop distress symptoms from bowel prep (and the type) between the two groups	20hours	Number of participants who develop distress symptoms from bowel prep, and the type of distress symptoms will be compared between the two groups
Difference in the absolute number/percentage of participants in the two groups who find the bowel prep experience easy, acceptable, difficult, very difficult, or unable to complete.	20hours	Participants will be asked to rate their bowel prep experience (based on ease of use) on a Likert scale. The number of participants in each level will subsequently be quantified (n, %) and compared between the two groups.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026