Health Benefits of Chronic vs. Acute Exercise in Overweight Adults

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01452087

Enrollment

Registered

2011-10-14

Start date

2009-05-31

Completion date

2014-10-31

Last updated

2014-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

insulin sensitivity, exercise

Brief summary

Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.

Interventions

OTHERExercise

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Body Mass Index: 27-34 kg/m2; * Regular exercisers(≥4 days/wk of aerobic exercise; * 30-60min/session at moderate and vigorous intensities); * Non-exercisers (no regularly planned exercise/physical activity); * Women must have regularly occurring menses and must be premenopausal.

Exclusion criteria

* Pregnant or lactating; * Evidence/history of cardiovascular or metabolic disease; * Currently taking medications known to affect lipid or glucose metabolism.

Design outcomes

Primary

Measure	Time frame
oral glucose tolerance test	2 hour

Secondary

Measure	Time frame
Resting Metabolic Rate	20-30 min

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026