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Human Skin Aging: Clinical Parameters and Gene Expression Profiling

Human Skin Aging: Clinical Parameters and Gene Expression Profiling

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01451476
Acronym
GEP
Enrollment
122
Registered
2011-10-13
Start date
2010-05-31
Completion date
2015-12-31
Last updated
2024-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ageing

Keywords

Ageing

Brief summary

Skin aging is a complex process involving genetic and environmental factors. The investigators hope to learn more about how human genes and their function can contribute to skin aging and human health.

Detailed description

This study includes answering a survey on prior sun exposures, donating two small pieces of skin (4mm each), one blood draw, complexion analysis, photographs, and non-invasive tests such as skin surface lipid analysis. Your blood and tissue will be sent for DNA analysis and gene expression profiling.

Interventions

None listed

Sponsors

Stanford University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* healthy female, age 18 or older, * Fitzpatrick type 1 or 2 skin, * able to read and understand written consent form, * body mass index normal or overweight range, * willing to take blood tests and donate skin samples

Exclusion criteria

* pregnant or lactating, * history of cosmetic surgery affecting the face, * use of prescription anti-aging medications for 2 weeks prior to study, * use of dietary supplements for 2 weeks prior to study, use of tanning beds or excessive light exposure (\>2 hours) in the past 2 weeks, * medical conditions which at the discretion of the investigator will have significant impact on ability to judge subjects' skin characteristics and age, sunless tanner use in past 2 weeks

Design outcomes

Primary

MeasureTime frame
Assessment of age related gene expression changes in skinCross sectional

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026