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Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction

Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01450917
Enrollment
245
Registered
2011-10-12
Start date
2009-09-30
Completion date
2009-10-31
Last updated
2011-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Paralysis

Brief summary

Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination. Thus the diaphragmatic elevation on chest radiograph is assumed to identify the phrenic nerve dysfunction. Normally, the right diaphragm is higher than the left side about 1.5 ± 0.9 centimeters or 0.5 ± 0.3 time of vertebral height. Although there are several methods to determine the diaphragmatic elevation from previous studies, the accuracy, reliability, intra and inter-observer variation are problem. Neurotization is the effective procedure to restore upper extremity function in root avulsion type. Phrenic nerve is one of the common donor nerves which used for this procedure. But sometimes, concomitant injury of this nerve can occur. Therefore, the investigators established Diaphragmatic height index (DHI) from chest radiograph to use as the diagnostic test for phrenic nerve dysfunction.

Interventions

None listed

Sponsors

Mahidol University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Brachial plexus injured patients who underwent the neurotization in our institute between 2005-2008 * Non brachial plexus injured patients who underwent the other orthopedic operation in our institute between April-June 2009

Exclusion criteria

* Concomitant pneumothorax and/or hemothorax * Concomitant pulmonary contusion * Previous pulmonary disease * Chest wall deformity * Thoracic or thoracolumbar scoliosis (\>10 degrees) * Hepatomegaly * Incomplete data

Design outcomes

Primary

MeasureTime frame
The cut-off point of DHI for diagnosis of phrenic nerve dysfunctionupto 3 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026