Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers

Comparison of the Efficacy of the Adductor-Canal-Blockade Versus the Femoral Nerve Block on Muscle Strength and Mobilization in Healthy Volunteers: a Randomized Study

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01449097

Enrollment

Registered

2011-10-07

Start date

2011-10-31

Completion date

2011-11-30

Last updated

2011-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers, Muscle Strength

Keywords

Adductor-Canal-blockade,, human volunteers,, US-guided nerve block, femoral nerve block

Brief summary

The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers. The investigators hypothesize that the Adductor-Canal-Blockade results in a lesser reduction of the quadriceps muscle strength compared to the femoral nerve block.

Interventions

PROCEDUREAdductor-Canal-Blockade

US-guided Adductor-Canal-blockade with Ropivacaine

PROCEDUREThe femoral nerve block

US-guided femoral nerve block with ropivacaine

PROCEDUREPlacebo

US-guided Adductor-Canal-Blockade/femoral nerve block with saline

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* written informed consent * ASA 1 * BMI \> 18 og \< 25

Exclusion criteria

* Can not cooperate to the exam * Do not speak or understand Danish * Drug allergy * Alcohol or drug abuse * Daily consumption of analgetics on prescription * Any drug intake within the last 48 hours * Neuromuscular defects in the femoral nere, the obturator nerve or the muscles of the thigh. * Previous surgery or trauma to the lower limb * Diabetes Mellitus * Intake of steroids, except steroids for inhalation * Physical exercise within the last 24 hours prior to Day 1 and 2 of the study

Design outcomes

Primary

Measure	Time frame
the difference in quadriceps muscle strength between the Adductor-Canal-Blockade and placebo	0-6 hours

Secondary

Measure	Time frame
The difference in quadriceps muscle strength between the Adductor-Canal-Blockade and the femoral nerve block	0-6 hours
The difference in quadriceps muscle strength between the placebo and the femoral nerve block	0-6 hours
The difference in adductor muscle strength between the groups	0-6 hours
The difference in mobilization between the groups	0-6 hours

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 24, 2026