Phenotypic Expressions in a French Pseudoxanthoma-Elasticum Cohort

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01446380

Enrollment

350

Registered

2011-10-05

Start date

2008-06-30

Completion date

2021-01-31

Last updated

2011-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pseudoxanthoma Elasticum

Brief summary

The cohort is intended to study the phenotypic expressions of the pseudoxanthoma elasticum (PXE) disease in various tissues (eye, skin, arteries, etc).

Detailed description

This national french cohort is intended to improve our knowledge on the PXE disease. The study of phenotypic expression of the diseases is focused on cutaneous, opthalmologic and vascular tissues. All investigations are included in a yearly follow-up for these patients and collected in a database. Plasma are also collected for all patients and stored in our clinical research biological center in Angers, including genetic (DNA) material extracted from diagnostic skin biopsy. French Ministry of Teaching and Research Authorisation number for the PXE collection is AC 2008 871. Declarative number is DC 2008 870.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients with PXE disease * Informed consent obtained * Patient affiliated to Health care system (french social security)

Exclusion criteria

* No informed consent * No affiliation to a Health care system

Countries

France

Contacts

Primary ContactLudovic MARTIN, MD PhD

LuMartin@chu-angers.fr33(2)41-35-34-19

Backup ContactGeorges LEFTHERIOTIS, MD-PHD

GeLeftheriotis@chu-angers.fr33(2)41-35-44-56

Outcome results